Chemotaxis: a complex netwerk of interconnecting signalling pathways and amplification loops

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Chemotaxis or directional movement towards a chemical compound is an essential property of many cells and fundamentally important for processes as diverse as the sourcing of nutrients by prokaryotes, the organisation of the embryo in metazoa, the formation of multicellular structures in protazoa and the migration of lymphocytes during immune response. Chemotaxis is also linked to the development and progression of many diseases including asthma, arthritis, atherosclerosis, and cancers. Therefore, further insight into the molecular mechanism of chemotaxis is important for the understanding of many biological processes.

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