A novel membrane protein insertion pathway in Escherichia coli

Every living cell is surrounded by a selectivity permeable cytoplasmic membrane. Its general structure is a lipid bilayer with embedded and peripherally associated membrane proteins. The primary functions of the cytoplasmic membrane are the regulation of cell volume and maintenance of the intracellular pH and the molecular composition of the cell's content. Membrane proteins fulfil a variety of vectorial transport, communication and energy transduction functions. They catalyze the import of ions and organic substrates for anabolic and catabolic reactions within the cell, the export of dissimilation products or toxic compounds and even the transport of macromolecules, like secretory proteins, without disturbing the general role of the membrane as a diffusion barrier for hydrophilic compounds and ions. ...

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