New Insight in Haloalkane Dehalogenase Kinetics and Evolution by Enzyme Engineering

Halogenated carbon compounds represent a major class of recalcitrant environmental pollutants. Even for many of these often xenobiotic chemicals, however, the highly dynamic and adaptive microbial world has managed to develop suitable degradation pathways. A particular critical step in the degradation pathway of organohalogens appears to be the cleavage of carbon-halogen bonds. ...

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