DNA recombination in plants : molecular and functional analysis of Arabidopsis RecQ genes

It is widely accepted that the maintenance of genome integrity is vital for cell survival. Cells with compromised genome integrity often exhibit defects in their response to DNA damage. As depicted in Figure 1, page 106, DNA damage may cause cell cycle arrest and programmed cell death. The latter prevents the transfer of incorrect DNA code to the next generation, whereas cell cycle arrest provides time for repair of the damage. One of the most important types of DNA damage that can activate programmed cell death, if not properly repaired, is DNA double strand break. DNA double strand breaks

	titlepages/contents
	chapter 1
	chapter 2
	chapter 3
	chapter 4
	chapter 5
	acknowledgements
	arabic summary
	curriculum vitae
	references
	samenvatting
	summary
	thesis

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