Functional markers for the assessment of (sub)clinical micronutrient deficiencies. Contributions to the diagnosis of hyperhomocysteinemia and essential fatty acid deficiency.

Nutrition plays an important role in the pathophysiology of (chronic) disease ( chapter" l) .
The rapidly dietary changes in the past century may at least in part be at the basis of the high risk of some typically Western diseases, including coronary heart disease (CHD), diabetes mellitus,certain cancers, chronicob structive pulmonary disease, dementia and
osteoporosi.

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