Prejunctional auto- and heteroregulation of autonomic neurotransmission in the airways

The autonomic nervous system controls many aspects of airway function, including airway smooth muscle tone, mucus secretion, and intrapulmonary vascular permeability and blood flow. The predominant control is provided by parasympathetic nerves, using acetylcholine (ACh) as the neurotransnitter, to give bronchoconstriction, enhanced mucus secretion, and
bronchial vasodilatation. Sympathetic innervation, using noradrenaline (NA) as the neurotransmitter, is generally much sparser. Sympathetic neurotransmission causes inhibition of mucus secretion, bronchial vasoconstriction, and relaxation of
airway smooth muscle. In addition to these classic components of the autonomic nervous system, airways receive non-adrenergic non-cholinergic (NANC) input. ...

Zie: Summary.

Summary

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