Aiming at the cirrhotic liver: drug targeting in practice.

In this thesis, we have explored the concept of drug targeting for the treatment of liver cirrhosis. This fatal disease is currently among the top ten causes of death in the Western World an can not be treated properly with drugs. The only effective treatment to date is a liver transplantation. The lack of donor organs and the complexity of the surgical procedures, however, prevent widespread use of this treatment. Pharmacological intervention has failed up until now because of insufficient uptake of drugs in the target cells or extrahepatic side-effects, or a combination of both. Organ or cell-specific targeting of drugs may circumvent these problems. ...

Zie: Summary conclusions and pefspectlves

Summary conclusions and pefspectlves

Meer informatie in de catalogus
Meer informatie in Picarta