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Construction and analysis of mixture-process variables designs as applied to tablet formulations

(1993) Duineveld, Cornelis Adriaan Antonius

This thesis is concerned with methods for the systematic optimization of pharmacutical formulations. Such methods are of interest for pharmaceutical industries. In order to limit the problem only one kind of formulation is examined. This is the direct compressed tablet. Several techniques which can be used for the optimization of a direct compressed tablet are described. This kind of tablet is made by mixing the ingredients (among which the pharmacon) for some time, addition of a lubricant and again mixing. From the resulting powder fixed portions are taken which are compressed in a die. ...

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ID	32418
Moeder ID	28666
Volgorde	duineveld.c.a.a.
Naam	c.a.a.duineveld
Publiceren	yes
OAI-naam	Dissertation
Path	faculties/science/1993/c.a.a.duineveld/
Gemodificeerd op:	2013-02-15 14:28:01
Digitaal ID	4938e5285cc01
Instelling	Faculty of Mathematics and Natural Sciences
Datum beschikbaarstelling	2008-12-04
Titel	Construction and analysis of mixture-process variables designs as applied to tablet formulations
Titelvolgorde	Construction and analysis of mixture-process variables designs as applied to tablet formulations
Elektronisch	no
Ruilverkeer mogelijk	no
Printen in opdracht	no
Exporteer?	yes
Aantal pagina's	175
Publicatiejaar	1993
Verslagjaar	2008
Taal	en
Type	Dissertation
Samenvatting EN	This thesis is concerned with methods for the systematic optimization of pharmacutical formulations. Such methods are of interest for pharmaceutical industries. In order to limit the problem only one kind of formulation is examined. This is the direct compressed tablet. Several techniques which can be used for the optimization of a direct compressed tablet are described. This kind of tablet is made by mixing the ingredients (among which the pharmacon) for some time, addition of a lubricant and again mixing. From the resulting powder fixed portions are taken which are compressed in a die. ... Zie: Summary
Uitgever	University of Groningen
Rechten	University of Groningen
PPN	112131719
Trefwoord GOO	Optimaliseren, Geneesmiddelen, Tabletten Proefschriften (vor;
Trefwoord NBC	toepassingen van de wiskunde; farmacologie (geneeskunde);
Auteur	Duineveld, Cornelis Adriaan Antonius;
Naamsvariant auteur(s)	Duineveld, Kees;
Promotors	Doornbos, D.A.; Smilde, A.K.;

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Construction and analysis of mixture-process variables designs as applied to tablet formulations