Sterol side chain cleavage by mycobacterium.

The selective microbial sterol side chain cleavage is an attractive way of converting cheap and abundantly available sterols inlo AD and ADD. These two compounds are excellent intermediates of high added value in the synthesis of nearly all steroid hormone drugs. Sterols of choice are the zoosterol cholesterol and phytosterols such as B-sitosterol, campesterol and stigmasterol. However, the microbial side chain cleavage
is characterized by some fundamental problems.

Zie: Summary and conclusions

Summary and conclusions

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