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(1989) Kaptein, Bernardus
In this thesis the synthesis of Zn2+ and Co2+ complexes with sulfur and nitrogen containing ligands as model compounds for the active site of Horse Liver Alcohol Dehydrogenase (HLADH) is described. HLADH is an enzyme which reversibly oxidizes alcohols to aldehydes or ketones, making use of the coenzyme NAD+/NADH. The active site of HLADH contains a
zinc ion, coordinated by two cysteines, a histidine and a water molecule (or hydroxide ion). This zinc ion is necessary for the catalytic activity of the enzyme. ...
Zie: Summary
Gebruik a.u.b. deze link om te verwijzen naar dit
document:
http://irs.ub.rug.nl/ppn/051444992 |
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| ID |
31765 |
| Moeder ID |
29537 |
| Volgorde |
kaptein.b |
| Naam |
b.kaptein |
| Publiceren |
yes |
| OAI-naam |
Dissertation |
| Path |
faculties/science/1989/b.kaptein/ |
| Gemodificeerd op: |
2013-02-15 14:28:01 |
| Digitaal ID |
48e343ff554d0 |
| Instelling |
Faculty of Mathematics and Natural Sciences |
| Datum beschikbaarstelling |
2008-09-30 |
| Titel |
Synthetic models for the active site of alcohol dehydrogenase. |
| Titelvolgorde |
Synthetic models for the active site of alcohol dehydrogenase. |
| Elektronisch |
no |
| Ruilverkeer mogelijk |
no |
| Printen in opdracht |
no |
| Exporteer? |
yes |
| Aantal pagina's |
147 |
| Publicatiejaar |
1989 |
| Verslagjaar |
2008 |
| Taal |
en |
| Type |
Dissertation |
| Samenvatting EN |
In this thesis the synthesis of Zn2+ and Co2+ complexes with sulfur and nitrogen containing ligands as model compounds for the active site of Horse Liver Alcohol Dehydrogenase (HLADH) is described. HLADH is an enzyme which reversibly oxidizes alcohols to aldehydes or ketones, making use of the coenzyme NAD+/NADH. The active site of HLADH contains a
zinc ion, coordinated by two cysteines, a histidine and a water molecule (or hydroxide ion). This zinc ion is necessary for the catalytic activity of the enzyme. ...
Zie: Summary |
| Uitgever |
University of Groningen |
| Rechten |
University of Groningen |
| PPN |
051444992 |
| Trefwoord GOO |
Alcoholdehydrogenase, Synthese (chemie), Modellen (theorie); Proefschriften (vorm); |
| Auteur |
Kaptein, Bernardus; |
| Naamsvariant auteur(s) |
Kaptein, Bernard; |
| Promotors |
Kellogg, R.M.; |
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