Vesicles from simple synthetic amphiphiles as membrane mimetic systems. Fusogenic and polymorphic behavior.

This thesis describes the first detailed study of the fusogenic behavior of vesicles prepared from simple synthetic amphiphiles. Fusion, an important and frequently occuring process in nature, involves the close apposition of two membranes that become transiently unstable and subsequently merge. It occurs during processes such as virus infection, cell division, as well as endo- and exocytosis. Because biological membranes have a complex composition, i.e. they consist of a variety of lipids and proteins, the mechanism of fusion has been studied frequently using simple model systems such as phospholipid vesicles (liposomes). Like biological membranes, vesicles formed from both natural and synthetic phospholipids consist of a bilayer of lipids that encloses an aqueous compartment. ...

Zie: Summary.

Summary

Meer informatie in de catalogus
Meer informatie in Picarta