Dissertaties - Rijksuniversiteit Groningen
 
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Optimization of the formulation of fast disintegrating tablets

(1987) Kamp, Herman Vincent van

Chapter 1 presents general information on tableting and is an introduction to the other chapters.
Chapter 2 covers the mechanism of action of tablet disintegrants, in particular modern super disintegrants. The results indicate that when the tablets contain a slightly swelling but hydrophilic disintegrant, the penetration of water into tablets is the controlling step in the process of disintegration. Consequently tablet disintegration is strongly affected by the presence of a hydrophobic lubricant. ...

Zie: Summary




file:Summary

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http://irs.ub.rug.nl/ppn/040429474

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