Bacterial contamination of surgical meshes

Dit document is (ook) beschikbaar voor ruilverkeer - alleen door bibliotheken -. [Bestelformulier]

The consequences of a biomaterial associated infection will generally follow a disastrous pattern regarding the subjected patient. In modern times post operative complications following abdominal wall reconstructive surgery are reduced to a minimum which, consequently, will result in a more prone position for infection as a complication.
Present studies suggest wide ranges of infection rates depending on the mesh morphology. This thesis presents a new experimental method to systematically investigate the progress of mesh related infections using non-invasive bio-optical techniques. A significant reduction of animals was seen. Comparative research showed significant differences in decease progress as a result of mesh morphology. In addition, using bio-optical imaging the number of animals was significantly reduced.
In future perspective, the results presented in this thesis will lead to improvements of surgical meshes and the currently presented experimental set-up could be used as an efficient and standardized evaluation protocol.

Meer informatie in de catalogus
Meer informatie in Picarta