The dynamic niche of the foreign body reaction : messages and messengers for regenerative medicine

Dit document is (ook) beschikbaar voor ruilverkeer - alleen door bibliotheken -. [Bestelformulier]

Intracorporally implanted materials, such as medical devices, will provoke the body to initiate an inflammatory reaction. This inflammatory reaction to implanted materials is known as the foreign body reaction (FBR) and is characterized by 3 distinct phases: onset, progression, and resolution. The FBR proceeds in the creation of a dynamic microenvironment that is spatially well organized. This reaction is regulated by soluble mediatiors, most likely cytokines, chemokines, and matrix metalloproteinases (MMPs), which are produced locally by surrounding tissue cells and infiltrating inflammatory cells.

Zie: Summary

Samenvatting

Meer informatie in de catalogus
Meer informatie in Picarta