Restenosis in clinical practice : modern risk factors and treatment options in patients at increased risk for coronary restenosis after balloon angioplasty and stenting

Despite considerable progress, restenosis remains a major limitation of percutaneous
coronary intervention (PCI). Restenosis is determined by many factors in which the ‘response
to injury’ plays a central role. There are two possible approaches in the prevention of
restenosis. Unraveling the complex pathophysiology of this vascular response has lead to a
better understanding of its mechanisms and to the identification of numerous risk factors.
This has lead to the development of new pharmacological and nonpharmacological treatment
options, with more or less success. Another approach is to prevent restenosis mechanically,
irrespective of its cause. Today, coronary stents are the corner stone of mechanical vessel
support, thereby also decreasing the restenosis rate in various subsets of patients at increased
risk.

	Title and contents
	Chapter 1
	Chapter 2
	Chapter 3
	Chapter 4
	Chapter 5
	Chapter 6
	Chapter 7
	Chapter 8
	Chapter 9
	Samenvatting
	Summary
	Dankwoord
	Curriculum Vitae
	Complete thesis

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