From Laboratory to Clinic: The study of a new cemented total hip arthroplasty

Aseptic loosening of total hip prostheses is still an unresolved problem, although the results of total hip arthroplasties have improved tremendously the last decade. Several mechanisms have been postulated to explain the failure of cemented total hip arthroplasties. Two dominant failure scenarios of cemented reconstructions can be identified: the accumulated-damage failure scenario; the cement and interfaces are not strong enough to resist the long-term dynamic loads, and the particulate-reaction failure scenario: the cement-bone interface gradually disintegrates due to the migration of wear particles. ....

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