Myocardial contractility and perfusion in healthy volunteers and patients with dilated cardiomyopathy

In this thesis some of the pathophysiological processes that are involved in heart failure,
especially due to idiopathic dilated cardiomyopathy,are described. Patients as well as healthy volunteers were investigated with two imaging techniques, positron emission tomography and dobutamine stress echocardiography. Myocardial perfusion and
b-adrenoceptordensity were measLrred with positron emission tomography while contractile responses were studied using dobutamine stress echocardiography.The
development of the techniques used for investigation of the subjects is reviewed and the results of the measurements in patients are described in this thesis.

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