On the mechanism of cationic amphiphile-mediated gene delivery.

Recombinant DNA techniques together with the mapping of the human genome have made it feasible to treat genetic disorders at their cause instead of treating the symptoms. Viruses are, exploiting their natural ability to enter cells and deliver their genes into the nucleus, used to deliver genetic material into mammalian cells to correct or the genetic disorders. However, the human body is likely to elicit an immune response against these viruses, which will limit the efficacy of the treatment and, moreover, may seriously endanger the patient's health.

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