Bacterial adhesion to contact lenses

Worldwide 85 million people use contact lenses (CL's) as an alternative to spectacles,. However, this large population is at risk and makes the use of CL's an important health concern, as CL wear can induce microbial keratitis, which may result in permanent visual loss. Bacteria adhere to the lens surface and form an infectious biofilm, depending on the physico-chemical surface properties determined by the bacterial cell, the lens and the suspending liquid. Different episodes of usage cycle in wearing the contact lens affect the physico-chemical properties of the lens surface and therefore influence the adhesion of bacteria, as outlined in Chapter 1. ...

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