Beta-adrenergic receptor imaging with positron emission tomography

In vivo quantification of β-adrenoceptors in the brain, heart and lung could be very valuable for the investigation of these receptors in neuropathologies, myocardial and pulmonary diseases, and for monitoring the effects of treatment. The aim of this thesis was the development of a method to image β-adrenoceptors in the human brain and heart with PET and the validation of a tracer kinetic model to in vivo quantify receptor densities....

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