Dissertaties - Rijksuniversiteit Groningen
 
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Cellular resistance to adriamycin and cisplatin: the role of detoxifying systems

(1993) Meyer, Jacoba

Adriamycin (Adr) and cisplatin (CDDP) play an important role in cancer chemotherapy. However, the frequent occurrence of resistance to these drugs represents a significant problem in the treatment of patients with cancer. A better understanding of the mechanisms involved in drug resistance may open ways to circumvent this problem and indicate possible targets for modulation of drug resistance. This thesis focuses on one of the possible mechanisms involved in cellular resistance to Adr and CDDP: the availability of cellular detoxifying systems which may be important determinant of resistance to Adr, CDDP and other chemotherapeutic drugs. ...

Zie: Summary, conclusions and perspectives




file:Summary, conclusions and perspectives

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ID 32500
Moeder ID 29010
Volgorde meyer.j.
Naam j.meyer
Publiceren yes
OAI-naam Dissertation
Path faculties/medicine/1993/j.meyer/
Gemodificeerd op: 2013-02-15 14:28:01
Digitaal ID 494626ab431f4
Instelling Faculty of Medical Sciences
Datum beschikbaarstelling 2008-12-14
Titel Cellular resistance to adriamycin and cisplatin: the role of detoxifying systems
Titelvolgorde Cellular resistance to adriamycin and cisplatin: the role of detoxifying systems
Elektronisch no
Ruilverkeer mogelijk no
Printen in opdracht no
Exporteer? yes
Aantal pagina's 132
Publicatiejaar 1993
Verslagjaar 2008
Taal en_US
Type Dissertation
Samenvatting EN Adriamycin (Adr) and cisplatin (CDDP) play an important role in cancer chemotherapy. However, the frequent occurrence of resistance to these drugs represents a significant problem in the treatment of patients with cancer. A better understanding of the mechanisms involved in drug resistance may open ways to circumvent this problem and indicate possible targets for modulation of drug resistance. This thesis focuses on one of the possible mechanisms involved in cellular resistance to Adr and CDDP: the availability of cellular detoxifying systems which may be important determinant of resistance to Adr, CDDP and other chemotherapeutic drugs. ...

Zie: Summary, conclusions and perspectives
Uitgever University of Groningen
Rechten University of Groningen
PPN 104037121
Trefwoord GOO Longkanker, Chemotherapie, Doxorubicine ,; Cisplatine, Resistentie; Proefschriften (vorm);
Trefwoord NBC neoplasmata, gezwellen;
Auteur Meyer, Jacoba;
Naamsvariant auteur(s) Meyer, Coby;
Promotors Mulder, N.H.;


 
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