Lithium. Effects on excitable cell membranes

LITHIUM: Effects on excitable cell membranes. Lithium salts have been used in the treatment of manic-depressive psychosis for many years but their mechanism of action is not well understood. Many workers assume that the action of lithium on catecholamine metabolism and/or on electrolyte distribution is in some way related with its therapeutic effect. Because lithium closely resembles sodium and potassium, we have studied the effect of lithium on phenomena which are controlled by sodium and potassium. ...

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Summary

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